tag:blogger.com,1999:blog-8948118800667522559.post5221995249483029064..comments2008-06-30T00:34:30.807-04:00Comments on Neuroscientifically Challenged: It's All About Timing: Circadian Rhythms and Behav...Marc Dingmanhttp://www.blogger.com/profile/14938086179275233750marcdingman@yahoo.comBlogger5125tag:blogger.com,1999:blog-8948118800667522559.post-69977372638244153572008-06-30T00:34:00.000-04:002008-06-30T00:34:00.000-04:00Thanks Pete, glad you enjoyed the post! I agree wi...Thanks Pete, glad you enjoyed the post! I agree with you, circadian rhythms are too integral an aspect of our lives not to have a big impact on our emotional state when they are disturbed.Marc Dingmanhttp://www.blogger.com/profile/14938086179275233750noreply@blogger.comtag:blogger.com,1999:blog-8948118800667522559.post-25532616516000233482008-06-29T11:24:00.000-04:002008-06-29T11:24:00.000-04:00I love concise, information-dense essays like this...I love concise, information-dense essays like this, and the fact that we have only stratched the surface of scietific knowledge re this topic. Chronobiology needs to be better known to non-scientists, since the sleep-wake cycle dominates almost everything we do...any variations have profound ramifications...PeteKhttp://www.blogger.com/profile/12009366232643063416noreply@blogger.comtag:blogger.com,1999:blog-8948118800667522559.post-76925184922591839002008-06-27T17:10:00.000-04:002008-06-27T17:10:00.000-04:00Thanks physioprof, I believe I was thinking of dro...Thanks physioprof, I believe I was thinking of drosophila when I used TIM. I made the correction.Marc Dingmanhttp://www.blogger.com/profile/14938086179275233750noreply@blogger.comtag:blogger.com,1999:blog-8948118800667522559.post-8754190211200132382008-06-27T13:17:00.000-04:002008-06-27T13:17:00.000-04:00One cause of the mutations that causes new-non-fam...One cause of the mutations that causes new-non-familial cases of developmental neurodevelopmental disorders is older paternal age. Sperm precursor cells collect mutations and pass them on to sperm. I don't know if this is of any interest. http://www.news.com.au/heraldsun/story/0,21985,23849196-5000117,00.htmlconcerned hearthttp://www.blogger.com/profile/14987948292416367555noreply@blogger.comtag:blogger.com,1999:blog-8948118800667522559.post-34874360661947867602008-06-27T11:24:00.000-04:002008-06-27T11:24:00.000-04:00You've got the TIM thing wrong. In current models ...You've got the TIM thing wrong. In current models of the mammalian clock, it is CRY, not TIM, that is thought to participate with PER in negative transcriptional feedback.PhysioProfhttp://physioprof.wordpress.com/noreply@blogger.com